Answer
Answer 14-12. Symptoms develop over days to weeks, usually resolving over weeks to months. It often proceeds in an ascending fashion though it may even start in the cranial nerves. It can paralyze all muscles (including respiration) and produce autonomic nervous system instability. Reflexes are lost early on, even in clinically unaffected muscles. Autonomic instability can be fatal as can respiratory arrest, infection or pulmonary embolus. Guillain-Barre syndrome does not effect central nervous system. Patients usually recover (about 20% have residual).