Answer
Answer 20-12. Surgical resection is possible for benign tumors like meningioma and sometimes for solitary metastasis (if the systemic cancer controllable). Chemotherapy is limited by the blood-brain barrier and only specific types can be used. Sometimes chemotherapeutic agents can be delivered to the intrathecal space. Radiation is often useful for treatment, but it can damage the brain, especially long-term. For example it may result in necrosis that looks like recurrent tumor. There are experimental approaches to block angiogenesis or immune targeting.